Distribution of main genomic aberration in ALK+ and ALK-ALCL and their impact on outcome. Heatmap with the relative distribution of the most common lesions detected in ALCL samples (A) and Kaplan-Meier graph showing OS in systemic ALCL according to ALK status and to the presence of PRDM1 inactivation and/or TP53 loss (B). In panel A: red, presence; gray, absence. In panel B: x-axis, months; y-axis, percentage of alive patients.