Hematologic parameters of Abcg8^−/− and Abcg5^−/− mice fed an Abcg8^−/− HS or Abcg8^−/− LS diet. (A) Platelet counts, (B) mean platelet volumes, and (C) hemoglobin values. Samples were analyzed using a Vet ABC Counter (n = 6 in each group); **P < .001. (D) Tail bleeding time assays of Abcg8^−/− mice fed an HS or LS diet. When bleeding did not cease within 5 minutes, the tail was cauterized and bleeding time was recorded as 300 seconds.