Expression patterns of HOXA7, HOXA9, HOXA11, PBX1, PBX2, PBX3, MEIS1, MEIS2, and MEIS3, and the expression correlations between HOXA9 and other genes. (A) The USA set^23,28  (including 9 MLL-rearranged, 31 t(15;17), 27 inv(16), 30 t(8;21) AML cases and 10 normal control samples); (B) the Germany set²⁹  (including 8 MLL-rearranged, 11 (−7)/7q, 4 (+8), 5 complex, 12 t(15;17), 15 inv(16), 11 t(8;21) AML, and 5 other CA-AML cases); (C) The Netherlands set³⁰  (including 16 MLL-rearranged, 5 t(6;9); 4 t(9;22), 18 (−3q), 18 (−7q), 31 (+8), 14 complex, 19 t(15;17), 38 inv(16), 37 t(8;21) AML, and 71 other CA-AML cases); and (D) the mouse bone marrow transplantation (BMT) set²⁸  (including 9 MLL-AF9 mouse leukemic BM cell samples and 6 normal control BM cell samples collected from primary or secondary BMT recipient mice), respectively. Pearson correlation was applied to analyze the correlation. Expression data were mean centered and the relative value for each sample is represented by a color, with red representing a high expression and green representing a low expression (scale shown in the top right).