Figure 2
![Figure 2. Scl is not required for Lmo2-driven leukemogenesis. (A) Kaplan-Meier survival curve of Lmo2-transgenic mice of the indicated genotypes. (P = .06 between SclΔ/+ and SclΔ/– using the log-rank [Mantel-Cox] test). (B) Deletion of Scl in hematopoietic tissues from a leukemic Lmo2;Lck;Scl mouse. Genomic DNA was extracted from the bone marrow (BM), spleen (SPL), and thymus (THY) of a leukemic Lmo2;Lck;SclΔ/– mouse and used in Southern hybridization to reveal null (–), floxed (fl), and deleted (Δ) Scl alleles.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/122/12/10.1182_blood-2012-09-458570/4/2093f2.jpeg?Expires=1726840173&Signature=AL0ha4pZARb93~8~F~P0DbVhyaj~2lbmOS9IWHenN2vAhJtbSumHpTao0nzwxBa1FNetzrcqxngGCzh4pNIiwT8gUNxSoyu-LI0aP1C~aUq-m570ddDBjycETeQMzd2iXcY1tXrdLPJmGPOuvuNP2HSjt~FlVyq2FvZnPK6caho98f8Cfgs022-QCI5ktADWjnrk7nIK4kFDOsPbJ0ZvC1V5~ELl5Aanx28bTINrKRamLvTdIZDu5e2WPYYyWfCl8EMcFhAdxzXj8hUJB2NjM3EONJEI52tpjzgR5lZ2Btmd3oNUqZUh9seHL5BJg~oeMAb5Zo7x9N-4AdPXugqGiA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Scl is not required for Lmo2-driven leukemogenesis. (A) Kaplan-Meier survival curve of Lmo2-transgenic mice of the indicated genotypes. (P = .06 between SclΔ/+ and SclΔ/– using the log-rank [Mantel-Cox] test). (B) Deletion of Scl in hematopoietic tissues from a leukemic Lmo2;Lck;Scl mouse. Genomic DNA was extracted from the bone marrow (BM), spleen (SPL), and thymus (THY) of a leukemic Lmo2;Lck;SclΔ/– mouse and used in Southern hybridization to reveal null (–), floxed (fl), and deleted (Δ) Scl alleles.
