Figure 2
Disruption of Peyer’s patches is due to a decrease in B-cell numbers. Mice were treated with poly(I:C) as in Figure 1. Lymphocyte subpopulations were analyzed by flow cytometry. Absolute cell numbers of lymphocyte subpopulations (A,C) and poly(I:C)-induced change of lymphocyte subpopulation frequency within all viable cells (B,D) (difference from untreated in %) in Peyer’s patches and PLNs were determined. Data indicate the mean value of n = 5 mice ± SEM and are representative of at least 3 independent experiments. Treg, regulatory T cells.
