Prognostic value of somatic gene mutations in adult T-ALL. (A) Kaplan-Meier survival curve in adult T-ALLs treated in the ECOG2993 clinical trial with or without NOTCH1/FBXW7 mutations. (B) Kaplan-Meier survival curve in adult T-ALLs treated in the ECOG2993 clinical trial with or without BCL11B mutations/deletions. (C) Kaplan-Meier survival curve in adult T-ALLs treated in the ECOG2993 clinical trial with or without DNMT3A mutations. (D) Kaplan-Meier survival curves in adult T-ALLs treated in the ECOG2993 clinical trial with or without IDH1/IDH2 mutations, treated in the ECOG2993 clinical trial.