Prevalence of hypertension, diabetes, SLE, and major depression following recovery from TTP. Black bars for pre-TTP data represent point prevalence for all 57 patients at the time of their initial diagnosis of TTP. Black bars for post-TTP data for hypertension, diabetes, and SLE represent point prevalence data for 43 (93%) of the 46 surviving patients who were assessed in 2011-2012, comparable to the 2-year cycles of NHANES point prevalence data. The black bar for major depression represents point prevalence data for 37 (80%) of the 46 surviving patients who were assessed in 2012. Gray bars represent expected prevalence based on the NHANES US reference population. Hatched bars represent lifetime prevalence from assessments over the entire follow-up period for 55 (96%) of the 57 surviving patients for whom post-TTP data were available. Lifetime prevalence proportions were hypertension (45%), diabetes (24%), and SLE (14%). Pre-TTP point prevalence of hypertension among patients (19%) was not different from the expected prevalence from the NHANES US reference population (16%; P = .442); post-TTP point prevalence among patients (40%) was greater than the expected prevalence of the NHANES US reference population (23%; P = .011). Both pre-TTP (9%) and post-TTP (14%) point prevalences of diabetes were not different from the expected prevalence of the NHANES US reference population (7%; P = .799; 10%; P = .439). Both pre-TTP (7%) and post-TTP (12%) point prevalences of SLE were greater than the expected prevalence of the NHANES US reference population (0.3%, indicated by the asterisk; P < .001). The post-TTP point prevalence of major depression (19%) was greater than the expected prevalence from the NHANES US reference population (6%; P = .005).