Figure 3
Figure 3. Summary of parameter estimates. Estimates of d* (A,C) and the average turnover rate p (B,D) of naive (A-B) and effector/memory (C-D) CD4+ (, gray circles) and CD8+ (▪, black squares) T cells, obtained by fitting the single-exponential model to the data collected during 1, 4, or 8 weeks of labeling. (E) Estimates of the average turnover rate of CD4+ (, gray circles) and CD8+ (▪, black squares) effector/memory T cells obtained by fitting a multiexponential model (describing 2 subpopulations) to the individual data sets (labeling for 1, 4, or 8 weeks; or prenatal labeling) and simultaneously to all data combined. Bars with whiskers represent the 95% CIs of the estimates obtained by bootstrapping the residuals.

Summary of parameter estimates. Estimates of d* (A,C) and the average turnover rate p (B,D) of naive (A-B) and effector/memory (C-D) CD4+ (, gray circles) and CD8+ (▪, black squares) T cells, obtained by fitting the single-exponential model to the data collected during 1, 4, or 8 weeks of labeling. (E) Estimates of the average turnover rate of CD4+ (, gray circles) and CD8+ (▪, black squares) effector/memory T cells obtained by fitting a multiexponential model (describing 2 subpopulations) to the individual data sets (labeling for 1, 4, or 8 weeks; or prenatal labeling) and simultaneously to all data combined. Bars with whiskers represent the 95% CIs of the estimates obtained by bootstrapping the residuals.

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