Ligand receptor and negative regulator expression in AML and NBM samples. (A) Representative dot plots illustrate 3 patterns of gp130 expression: (left) uniformly low, (center) uniformly high, or (right) distinct high and low gp130 subpopulations. (B) Waterfall plot demonstrates the range of expression of G-CSFR. (C) Waterfall plot demonstrates the range of expression of gp130. The red bars with asterisks indicate the values for 9 normal bone marrow samples that were analyzed similarly. Bar values represent the percentage of events in the positive region. (D) Representative immunoblots illustrate SOCS3 and SHP1 expression levels in AML samples, NBM, and the internal control AML cell line Kasumi-1.