Clustering diagrams indicating reproducibility of replicate samples. (A) Definitive erythroid lineages cluster more closely to each other than to the primitive erythroid lineage. (B) Reproducibility of primitive and BM definitive erythroid sample replicates clearly separates the replicates by maturational stage. Fetal definitive erythroid replicate samples are less clearly resolved, with only the reticulocyte stage clearly separated from the erythroblast stages. P indicates proerythroblast; B, basophilic erythroblast; O, polychromatophilic/orthochromatic erythroblasts; and R, reticulocyte.