Interaction of M420del and M408V SNPs and their correlation with treatment failure. The median follow-up was 57 months. Patients were grouped according to their genotype at both SNPs as: no M420 deletion and none or 1 copy of M408V (M420/M408); M420 deletion and none or 1 copy of M408V (M420del/M408); no M420 deletion and 2 copies of M408V (M420/M408V); or M420 deletion and 2 copies of M408V (M420del/M408V). The number of patients at different time points is included under each 20-month follow-up point. There was insufficient information (n = 2) to prepare a cumulative incidence plot for the M420del/M408V genotype group. The P value is from global tests comparing survival across all genotype groups.