Mechanical injury of the aorta in control mice and mice with reduced platelet counts. (A) The abdominal aorta was mechanically injured using a forceps (compression for 15 seconds), and then blood flow was monitored by an ultrasonic flow probe for 30 minutes. The horizontal line indicates the mean time to vessel occlusion. Each symbol represents 1 animal (n.s., not significant, *P < .05; **P < .01; ***P < .001). (B) Representative blood flow measurements are shown.