Kaplan-Meier survival estimates according to DNMT3A mutational status. Data are shown for (A) RFS and (B) OS in the entire cohort; (C) RFS, and (D) OS in cytogenetically-normal (CN)-AML; (E) RFS, and (F) OS in the European LeukemiaNet (ELN) favorable and unfavorable CN-AML subgroups. fav, favorable; mut, mutated; unfav, unfavorable; wt, wild-type.