Ldb1 complexes bind at sites near those for Klf1. (A) GATA and CACC consensus motifs identified within Ldb1 complex–bound DNA fragments by MEME de novo motif search. (B) Overlap of the Klf1 binding sites from Tallack et al⁶  with Ldb1 complex (Ldb1/Tal1/Gata1) binding sites or with non-Ldb1/Tal1-associated Gata1-only binding sites. (C-H) UCSC Genome browser shots showing colocalized Ldb1, Tal1, Gata1, and Klf1 binding sites at (C) Ermap, (D) Slc22a4, (E) E2f2, (F) E2f4, (G) Gypa, and (H) Slc25a37 (positions of known cis-regulatory elements are indicated). Numbers on y-axis are number of sequence reads. Tracks for H3K27ac, H3K4me1, and p300 in MEL cells and mammalian conservation tracks are shown at the bottom.