Adhesion of GD and CTR RBCs to purified laminin α5 under flow conditions. (A) Blood samples were from 18 healthy CTRs and 18 GD patients. Number of RBCs remaining adherent to purified laminin α5-coated microslide after inflow at 0.3 dyn/cm² and washout at increasing shear stresses. Bars denote SEM (*P < .05; **P < .01; Mann-Whitney test). (B) Increased GD RBC adhesion compared with CTR RBCs is specific to laminin α5 and not to fibronectin (after inflow at 0.2 dyn/cm² and increasing washout until 1 dyn/cm², P < .01; ANOVA followed by Dunn multiple comparison test). Blood samples were from 4 healthy CTRs and 4 GD patients. GD RBCs were more adherent to laminin than CTR RBCs.