The heat map represents co-occurrence of MYD88 L265P mutation with other genetic alterations analyzed in 46 patients with WM using SNP array, cytogenetic analysis, and FISH. We have used Tmev software.¹⁵  Each row corresponds to key regulator genes of the canonical and noncanonical NF-κB pathways targeted by CNA, UPD, or mutation in WM. The columns represent individual patients color coded on the base of gene status. Each patient is represented by a virtual column (black mutation, deletion or gain of gene; gray, wild-type).