Figure 5
Figure 5. PARP1 inhibition decreases ZFN-mediated translocations in cells of hematopoietic origin. Jurkat cells were treated with olaparib or rucaparib, and translocations induced by ZFN pairs were measured by assaying der[3] formation by using semiquantitative PCR at the indicated times, as shown in Figure 4.

PARP1 inhibition decreases ZFN-mediated translocations in cells of hematopoietic origin. Jurkat cells were treated with olaparib or rucaparib, and translocations induced by ZFN pairs were measured by assaying der[3] formation by using semiquantitative PCR at the indicated times, as shown in Figure 4.

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