Sequential CNA analysis of TAM-derived cells in the recipients of patient 1. DNA obtained from the original patient sample and sorted hCD45⁺ recipient BM cells were analyzed by Affymetrix GeneChip Mapping 250K arrays and compared with the PB sample of the original patient in complete remission phase. The primary sample of the patient in TAM phase (blast 92%) had no CNA. hCD45⁺ BM cells of 1° to 7° recipients had a hemi-allelic deletion in regions 16q22 and 16q24 (black arrows). The 3° recipient had a gain of the entire arm of chromosome 1q (white arrow) in addition to deletion of 16q22 and 16q24. Arrowhead indicates abnormal CNA.