Changes in the frequencies of T-cell maturational phenotypes during maraviroc intensification. Estimated mean changes in naive (CD45RA+CCR7+) (A-B), central memory (CD45RA–CCR7+) (C-D), effector memory (CD45RA–CCR7–) (E-F), and terminally differentiated effector memory (TEMRA) (CD45RA+CCR7–) (G-H) CD4+ (A,C,E,G) and CD8+ (B,D,F,H) T-cell frequencies in peripheral blood (with 95% CI) are plotted for maraviroc-treated (red) and placebo-treated (blue) subjects over time. P values are provided for the changes within each indicated interval both within arms and between arms.