Figure 2
Elevated expression of Trib2 in PML-RARα–positive leukemias is associated with FLT3-TKD but not FLT3-ITD mutations. Expressions of Trib1 and Trib2 in (A) different FAB subtypes and (B) between PML-RARα– positive and –negative leukemias were examined by using the LGA based on the gene expression data set from Valk et al.9 (C) Trib2 expression in PML-RARα–positive leukemias was further stratified based on FLT3-ITD and -TKD mutation status and compared with that of PML-RARα–negative leukemias.
