Gene expression profiles and GSEA analysis of CD30⁺ vs CD30^– DLBCL. (A) Comparison of gene expression profiles between CD30⁺ and CD30^– DLBCL. (B) GSEA for differentially expressed genes of cytokine and TNFR pathways was performed on Kyoto Encyclopedia of Genes and Genomes pathway gene sets using all the probe sets that are associated with a known gene. The gene sets with a false discovery rate q value <0.05 after performing 1000 permutations were considered to be significantly enriched.