IL-7 administration increases the absolute number of CD4⁺T cells harboring integrated HIV DNA. (A) Fold changes in the frequencies of CD4⁺ T cells expressing Ki67, PD-1, and HLA-DR, 4 and 28 days following IL-7 administration as measured by flow cytometry. (B) Frequency of CD4⁺ T cells harboring integrated HIV DNA at baseline and 28 days after IL-7 administration. (C) Number of CD4⁺ T cells harboring integrated HIV DNA per milliliter of blood at baseline and 28 days after IL-7 administration. (D) Change from baseline in the absolute number of integrated HIV DNA copies per milliliter of blood in subjects who received IL-7 and in placebo controls. (E) Correlation between the change in CD4⁺ T-cell numbers and the increase in the frequency of cells harboring HIV integrated DNA per milliliter of blood.