IL-7 enhances viral production in productively infected cells but does not disrupt HIV latency. (A) Quantification of viral production in cell-culture supernatants of CD4⁺ T cells isolated from 7 viremic untreated HIV-infected subjects. Similar methods than in Figure 1A were used. (B) Correlation between the levels of spontaneous viral production and viral production induced by IL-7 in CD4⁺ T cells isolated from 7 viremic subjects. (C) Viral production in total CD4⁺ T cells and highly pure resting memory CD4⁺ T cells following stimulation with IL-7 and CD3/CD28 in 4 virally suppressed subjects.