American Society of Hematology

Figure 4

$SNP rs2897047 association with log2 AUC in LCLs and association with MRD and RFS in all AML patients. Association of SNP rs2897047 with (A) log2 AUC for cellular sensitivity to cytarabine in a cell-based model (meta-analysis P = 4.06 × 10−6) illustrated in CEU, YRI, and ASN; (B) MRD at day 22 in all AML patients (P = .0218), where the numbers in each box represent MRD levels <0.1, 0.1 to 1, or ≥1 and the numbers in parentheses indicate fraction of patients within each MRD category; and (C) RFS (P = .043) in all AML patients.$

SNP rs2897047 association with log2 AUC in LCLs and association with MRD and RFS in all AML patients. Association of SNP rs2897047 with (A) log2 AUC for cellular sensitivity to cytarabine in a cell-based model (meta-analysis P = 4.06 × 10⁻⁶) illustrated in CEU, YRI, and ASN; (B) MRD at day 22 in all AML patients (P = .0218), where the numbers in each box represent MRD levels <0.1, 0.1 to 1, or ≥1 and the numbers in parentheses indicate fraction of patients within each MRD category; and (C) RFS (P = .043) in all AML patients.

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