Figure 7
Figure 7. Plasma cells in MCL tumors are SOX11 negative. (A) MCL with focal plasmacytic differentiation. Some cells show Dutcher bodies corresponding to the accumulation of restricted immunoglobulins (arrow) (H&E; ×60). (B-C) Tumor cells expressing restricted kappa light chain and BLIMP1 (×60). (D) Tumor cells expressing cyclin D1 (×60). (E) SOX11 expression is negative in the tumor cells but positive in internal controls such as endothelial and histiocytic cells (×60). Arrows point to tumor cells with Dutcher bodies.

Plasma cells in MCL tumors are SOX11 negative. (A) MCL with focal plasmacytic differentiation. Some cells show Dutcher bodies corresponding to the accumulation of restricted immunoglobulins (arrow) (H&E; ×60). (B-C) Tumor cells expressing restricted kappa light chain and BLIMP1 (×60). (D) Tumor cells expressing cyclin D1 (×60). (E) SOX11 expression is negative in the tumor cells but positive in internal controls such as endothelial and histiocytic cells (×60). Arrows point to tumor cells with Dutcher bodies.

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