Figure 6
The proportion of mDCs in sLNs of day 12 rapΔ/Δ mice is elevated. FACS analysis of epidermis (A), dermis (B), and sLNs (C-D) of day 12 rapfl/fl and rapΔ/Δ littermates. Cells are gated on CD45+ (A), CD45+ MHC-II+ CD11c+ (B), lymphocytes (C), or MHC-IIhigh CD11cint mDC (D). Numbers and bar graphs indicate mean frequency ± SEM of cells in the respective gate or quadrant (N = 5 mice for rapfl/fl and N = 3 mice for rapΔ/Δ).

The proportion of mDCs in sLNs of day 12 rapΔ/Δ mice is elevated. FACS analysis of epidermis (A), dermis (B), and sLNs (C-D) of day 12 rapfl/fl and rapΔ/Δ littermates. Cells are gated on CD45+ (A), CD45+ MHC-II+ CD11c+ (B), lymphocytes (C), or MHC-IIhigh CD11cint mDC (D). Numbers and bar graphs indicate mean frequency ± SEM of cells in the respective gate or quadrant (N = 5 mice for rapfl/fl and N = 3 mice for rapΔ/Δ).

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