Figure 5
Figure 5. Scott syndrome platelets display normal convulxin (Cvx)-/thrombin (Thr)-induced Ca2+ responses. (A-B) Time drive of fluorescence increase of washed control (A) and Scott syndrome (B) platelets loaded with Fluo-4 and activated by Cvx/Thr (70 ng/mL, 4 nM) in the presence of 2 mM CaCl2. (C) Average change in mean fluorescence intensity (MFI), representing cytosolic Ca2+, after 10 min stimulation. n.s., not significant.

Scott syndrome platelets display normal convulxin (Cvx)-/thrombin (Thr)-induced Ca2+ responses. (A-B) Time drive of fluorescence increase of washed control (A) and Scott syndrome (B) platelets loaded with Fluo-4 and activated by Cvx/Thr (70 ng/mL, 4 nM) in the presence of 2 mM CaCl2. (C) Average change in mean fluorescence intensity (MFI), representing cytosolic Ca2+, after 10 min stimulation. n.s., not significant.

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