Figure 4
Figure 4. Hematologic toxicity using 211At-B10-30F11 and BMT. Nonleukemic SJL/J mice were injected with 0.67 nmol of B10-30F11 labeled with either 12 (●) or 24 (♦) µCi 211At. Control mice were given 24 µCi 211At-B10-rat IgG (♢) or BMT alone (○). Mice were bled at 1, 2, 3, 4, 6, 8, and 26 weeks to assay for (A) white blood cells (WBCs), (B) hemoglobin, and (C) platelets. Dashed lines indicate the range of normal control values.

Hematologic toxicity using 211At-B10-30F11 and BMT. Nonleukemic SJL/J mice were injected with 0.67 nmol of B10-30F11 labeled with either 12 (●) or 24 (♦) µCi 211At. Control mice were given 24 µCi 211At-B10-rat IgG (♢) or BMT alone (○). Mice were bled at 1, 2, 3, 4, 6, 8, and 26 weeks to assay for (A) white blood cells (WBCs), (B) hemoglobin, and (C) platelets. Dashed lines indicate the range of normal control values.

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