Scatterplot of bleeding scores and VWF:RCo/VWF:Ag ratios for type 1 VWD subjects. Bleeding scores are plotted on the left y-axis and VWF:RCo/VWF:Ag ratios are plotted on the right y-axis. White circles represent subjects with the D1472H sequence variation and black circles represent subjects without the D1472H sequence variation.