Pie chart illustrating the genetic heterogeneity and coexistence of the distinct secondary genetic abnormalities in AML with inv (16). The chart is based on 166 patients with complete cytogenetic data and complete mutation status on KIT, FLT3, NRAS, and KRAS. Among the secondary chromosome aberrations, trisomy 22 (+22) and trisomy 8 (+8) are indicated; all other secondary chromosome aberrations constitute 1 group abbreviated in the chart as “o.c.a.” Because of the rounding error, all values do not add up to exactly 100%.