Figure 8
Figure 8. Quantitation of fluorescence associated with PDI and platelets in 4 transplanted mouse cohorts. The median integrated platelet (A) and PDI (B) fluorescence (F) after infusion of anti-GPIb antibody and anti-PDI antibody in each of the transplanted mice is presented over a time course of 240 seconds after vessel wall injury. 1 indicates WT/WT (n = 25 thrombi); 2, WT/β3− (n = 28 thrombi); 3, β3−/WT (n = 26 thrombi); and 4, β3−/β3− (n = 26 thrombi; donor/recipient).

Quantitation of fluorescence associated with PDI and platelets in 4 transplanted mouse cohorts. The median integrated platelet (A) and PDI (B) fluorescence (F) after infusion of anti-GPIb antibody and anti-PDI antibody in each of the transplanted mice is presented over a time course of 240 seconds after vessel wall injury. 1 indicates WT/WT (n = 25 thrombi); 2, WT/β3 (n = 28 thrombi); 3, β3/WT (n = 26 thrombi); and 4, β3/β3 (n = 26 thrombi; donor/recipient).

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