Figure 4
Figure 4. The inhibitory effect of anti-ATP synthase β-chain antibodies on HIV-1 transfer is not affected by the cell line in which the virus is propagated. HIV-1 MN was propagated in the different T-cell lines as indicated. MDDC-mediated viral transfer activity to target TZM cells was measured as described in “Measuring transfer of HIV-1 to target cells by APCs.” A total of 100% transfer activity was determined for each cell line as the maximal transfer activity obtained in the absence of added antibody (No Ab).

The inhibitory effect of anti-ATP synthase β-chain antibodies on HIV-1 transfer is not affected by the cell line in which the virus is propagated. HIV-1 MN was propagated in the different T-cell lines as indicated. MDDC-mediated viral transfer activity to target TZM cells was measured as described in “Measuring transfer of HIV-1 to target cells by APCs.” A total of 100% transfer activity was determined for each cell line as the maximal transfer activity obtained in the absence of added antibody (No Ab).

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