Characteristics of ParaHox genes. (A) Chromosomal location of human ParaHox genes. Chromosomal locations of murine ParaHox genes are given in brackets. The direction of transcription is indicated by an arrow. (B) Protein structure of ParaHox genes; shown is the protein structure depicting the N-terminal transactivation domain (blue), the Pbx-interacting motif (PIM; brown), the HD (green), and validated phosphorylation sites (orange).