CCR8 expression is enriched on skin-resident memory T cells. (A) Representative dot plots showing CCR8 expression by total lymphocytes (left) or gated CD3⁺ T cells (right) isolated from peripheral blood (top panels) or normal human skin tissue (bottom panels). (B) The percentage of naive (CD45RA⁺CCR7⁺), central memory (CD45RA⁻CCR7⁺; Tcm), effector memory (CD45RA⁻CCR7⁻; Tem), or RA-expressing T effector memory (CD45RA⁺CCR7⁻; Temra) within gated CD4⁺CCR8⁺ (left) or CD8⁺CCR8⁺ T cells (right) from peripheral blood (n = 7; top panels) or skin tissue (n = 6; bottom panels). Horizontal lines indicate the median. (C) Representative histograms for CLA, CCR4, integrin β7, and CCR9 expression by gated CD3⁺CCR8⁺ peripheral blood T cells. (D) Representative histograms for CCR10 expression by gated CD3⁺CCR8⁺ peripheral blood (top) or skin-resident T cells (bottom).