Figure 1
Figure 1. Tabular data. Thrombocytopenic and normal platelet count donor and recipient pair clinical characteristics and mutation screening results. (A-F) Median telomere length (in kb) in donor 3 plotted versus age. Lines on the graph represent telomere length measurement ranges in normal controls: blue line indicates the 99th percentile; top green line, the 90th percentile; middle green line, the 50th percentile; bottom green line, the 10th percentile; and red line, the 1st percentile. The telomere length reference ranges according to population age are: very short (< 1st percentile), short (≥ 1st and < 10th percentile), and normal (≥ 10th and < 90th percentile). All donors had ANKRD26 SNV rs7897309 (c.59A>G) and donor 5 had SNV rs41299222 (c.-140C>G). *Also had a history of follicular lymphoma; @Follicular lymphoma recurred 4 years post-allogeneic hematopoietic stem cell transplant #Donor 6 was excluded from mutation analysis due to lack of a family member with hematopoietic malignancy. #Other includes: multiple myeloma, pure red cell aplasia, Hodgkin lymphoma, paroxysmal nocturnal hemoglobinuria, chronic lymphocytic leukemia, myelofibrosis, aplastic anemia, and renal cell carcinoma. !All P values determined by Wilcoxon rank-sum test. AA indicates aplastic anemia; ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; APL, acute promyelocytic leukemia; CML, chronic myeloid leukemia; dash (-), test not done; Hb, hemaglobin; MDS, myelodysplastic syndrome; MCV, mean corpuscular volume; MF, myelofibrosis; MPV, mean platelet volume; NA, data not available; NHL, non-Hodgkin lymphomia; PB, peripheral blood; PT, posttransplant; RCC, renal cell carinoma; SD, standard deviation; WBC, white blood cell count; and WT, wild-type.

Tabular data. Thrombocytopenic and normal platelet count donor and recipient pair clinical characteristics and mutation screening results. (A-F) Median telomere length (in kb) in donor 3 plotted versus age. Lines on the graph represent telomere length measurement ranges in normal controls: blue line indicates the 99th percentile; top green line, the 90th percentile; middle green line, the 50th percentile; bottom green line, the 10th percentile; and red line, the 1st percentile. The telomere length reference ranges according to population age are: very short (< 1st percentile), short (≥ 1st and < 10th percentile), and normal (≥ 10th and < 90th percentile). All donors had ANKRD26 SNV rs7897309 (c.59A>G) and donor 5 had SNV rs41299222 (c.-140C>G). *Also had a history of follicular lymphoma; @Follicular lymphoma recurred 4 years post-allogeneic hematopoietic stem cell transplant #Donor 6 was excluded from mutation analysis due to lack of a family member with hematopoietic malignancy. #Other includes: multiple myeloma, pure red cell aplasia, Hodgkin lymphoma, paroxysmal nocturnal hemoglobinuria, chronic lymphocytic leukemia, myelofibrosis, aplastic anemia, and renal cell carcinoma. !All P values determined by Wilcoxon rank-sum test. AA indicates aplastic anemia; ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; APL, acute promyelocytic leukemia; CML, chronic myeloid leukemia; dash (-), test not done; Hb, hemaglobin; MDS, myelodysplastic syndrome; MCV, mean corpuscular volume; MF, myelofibrosis; MPV, mean platelet volume; NA, data not available; NHL, non-Hodgkin lymphomia; PB, peripheral blood; PT, posttransplant; RCC, renal cell carinoma; SD, standard deviation; WBC, white blood cell count; and WT, wild-type.

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