Figure 8
Figure 8. Lack of osteoblastic N-cadherin does not inhibit the ability of PTH treatment to increase trabecular bone or HSC subsets. (A-C) Micro-CT analysis of trabecular bone from the femur of VEH- and PTH-treated WT and OB-NCadh mice: (A) trabecular bone volume/total volume, (B) trabecular number, and (C) trabecular spacing. (D-F) Frequency of LSK (D), ST-HSCs (E), and LT-HSCs (F), as defined in Figure 2 in the BM of WT and OB-NCadh mice treated with VEH or PTH. *P < .05. **P < .01. ***P < .001. Each dot indicates an individual mouse.

Lack of osteoblastic N-cadherin does not inhibit the ability of PTH treatment to increase trabecular bone or HSC subsets. (A-C) Micro-CT analysis of trabecular bone from the femur of VEH- and PTH-treated WT and OB-NCadh mice: (A) trabecular bone volume/total volume, (B) trabecular number, and (C) trabecular spacing. (D-F) Frequency of LSK (D), ST-HSCs (E), and LT-HSCs (F), as defined in Figure 2 in the BM of WT and OB-NCadh mice treated with VEH or PTH. *P < .05. **P < .01. ***P < .001. Each dot indicates an individual mouse.

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