Lack of osteoblastic N-cadherin results in decreased mineralized trabecular BV/TV and cortical thickness at 1 year of age. (A-C) Quantitative analysis of micro-CT scans depicting trabecular BV/TV (A), trabecular connectivity density (B), and cortical thickness (C). *P < .05. **P < .01. n = 3 or 4 male mice per group. (D) Representative micro-CT scans of the distal femur (top), knee joint and proximal tibia (bottom), of WT (left) and OB-NCadh (right) mice. (E) Representative micro-CT scans of trabecular bone at the metaphysis of the femur (top) or tibia (bottom) of WT (left) and OB-NCadh (right) mice. (F) Representative micro-CT scans of femur cortical bone from WT (left) and OB-NCadh (right) mice. (G-H) Quantitation of serum CTX (G) and tartrate-resistant acid phosphatase (H) levels in 1-year-old mice. Each dot represents an individual mouse; data are mean ± SEM.