Figure 2
Figure 2. Blockade of PD-L1, but not other inhibitory molecules, rescues FH cells from deletion. (A) Representative and (B) cumulative data of Thy1.2 FH cells transferred into Thy1.1 tyrosinase+ mice, tyrosinase+ mice treated with blocking antibodies against inhibitory ligands, or antigen-free albino mice. LNs were harvested 7 days postadoptive transfer. (A) Boxes represent the percentage of TCD8 that are Thy1.2+ FH cells in the LNs of recipient mice. Data represent 4 to 8 mice per condition from 2 to 8 independent experiments. (B) **P = .0049, ##P = .0021 (2-tailed, unpaired t test; error bars, SEM).

Blockade of PD-L1, but not other inhibitory molecules, rescues FH cells from deletion. (A) Representative and (B) cumulative data of Thy1.2 FH cells transferred into Thy1.1 tyrosinase+ mice, tyrosinase+ mice treated with blocking antibodies against inhibitory ligands, or antigen-free albino mice. LNs were harvested 7 days postadoptive transfer. (A) Boxes represent the percentage of TCD8 that are Thy1.2+ FH cells in the LNs of recipient mice. Data represent 4 to 8 mice per condition from 2 to 8 independent experiments. (B) **P = .0049, ##P = .0021 (2-tailed, unpaired t test; error bars, SEM).

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