Functioning of angiogenic neutrophils within the graft. The grafted tissues release VEGF-A that recruits a specific subset of angiogenic neutrophils from blood into the graft (1). The extravasated neutrophils (2) infiltrate the graft where they release MMP-9 (matrix metalloproteinase 9; (3) facilitating angiogenesis: development of a new capillary network (4) rescuing the graft from hypoxia.

Functioning of angiogenic neutrophils within the graft. The grafted tissues release VEGF-A that recruits a specific subset of angiogenic neutrophils from blood into the graft (1). The extravasated neutrophils (2) infiltrate the graft where they release MMP-9 (matrix metalloproteinase 9; (3) facilitating angiogenesis: development of a new capillary network (4) rescuing the graft from hypoxia.

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