Figure 2
Figure 2. Peripheral CD4+ T cells expressing CXCR3 are reduced in cGVHD. Shown is T-cell chemokine receptor expression in the peripheral blood of patients after allogeneic SCT. Shown are the results of flow cytometric analysis of cell-surface expression of CXCR3-PE (A), CCR4-PE-Cy7 (B), CCR6-PerCPCy5.5 (C), and CCR10-APC (D) on CD4+ and CD8+ T cells in control SCT patients (n = 5) and in SCT patients with cGVHD (n = 5). Data are shown as the frequency of total peripheral CD4+ and CD8+ T cells expressing each receptor in individual donors, with bars indicating mean expression levels for each group. *P < .05 by the Mann-Whitney U test.

Peripheral CD4+ T cells expressing CXCR3 are reduced in cGVHD. Shown is T-cell chemokine receptor expression in the peripheral blood of patients after allogeneic SCT. Shown are the results of flow cytometric analysis of cell-surface expression of CXCR3-PE (A), CCR4-PE-Cy7 (B), CCR6-PerCPCy5.5 (C), and CCR10-APC (D) on CD4+ and CD8+ T cells in control SCT patients (n = 5) and in SCT patients with cGVHD (n = 5). Data are shown as the frequency of total peripheral CD4+ and CD8+ T cells expressing each receptor in individual donors, with bars indicating mean expression levels for each group. *P < .05 by the Mann-Whitney U test.

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