Genetic profiles and treatment response of patients. Each column represents 1 patient (n = 161) and each row 1 particular genetic parameter or treatment response (last row). The histogram on the right summarizes the % frequency of patients who presented with the row parameter in our study cohort. Color code: gray, parameter not available; white, parameter not present; any other color, parameter present. First row (number of mutated genes): white = 0 genes mutated; yellow = 1 gene mutated; light orange = 2 genes mutated; orange = 3 genes mutated; brown = 4 and more genes mutated.