Figure 6
Figure 6. Correlation between the percentage of infected MoDCs and the percentage of mature MoDCs in the presence of HIV-1–specific Abs. Curve for the correlation between the percentage of infected MoDCs (with respect to control) and the fold increase in the percentage of CD83+ DC-SIGN+ MoDCs for each Ab concentration (100 μg/mL and serial 2-fold dilutions, as in Figure 4). Anti-gp120 NAbs b12 (A) and 2G12 (B); anti-gp41 NAbs 4E10 (C) and 2F5 (D); and NNAbs 246-D (E) and 4B3 (F). Data are the means ± SD of at least 5 independent experiments performed with cells from different healthy blood donors. Correlations were analyzed by calculating the Pearson correlation coefficient, with P < .05 considered significant.

Correlation between the percentage of infected MoDCs and the percentage of mature MoDCs in the presence of HIV-1–specific Abs. Curve for the correlation between the percentage of infected MoDCs (with respect to control) and the fold increase in the percentage of CD83+ DC-SIGN+ MoDCs for each Ab concentration (100 μg/mL and serial 2-fold dilutions, as in Figure 4). Anti-gp120 NAbs b12 (A) and 2G12 (B); anti-gp41 NAbs 4E10 (C) and 2F5 (D); and NNAbs 246-D (E) and 4B3 (F). Data are the means ± SD of at least 5 independent experiments performed with cells from different healthy blood donors. Correlations were analyzed by calculating the Pearson correlation coefficient, with P < .05 considered significant.

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