Proximal KIR promoter activities in CD8 T cells and NK cells. (A) Relative ratios between sense (coding) and antisense transcripts from bidirectional proximal KIR promoters are depicted for YT-Indy (NK cell–derived) and Jurkat (T cell–derived) cells transfected with vectors containing proximal promoter regions from the indicated KIRs together with luciferase. Mean ± SD of 5 experiments are shown. (B) Sense (coding) and antisense transcripts generated from the bidirectional KIR3DL1 proximal promoter are depicted as relative expression ratio for total NK cells and CD8 T cells as well as for KIR3DL1⁺ and KIR3DL⁻ NK cells and CD8 T cells. One representative individual of 2 investigated is shown.