Rapamycin prolongs survival of JAK-mutated ALL xenografts. Kaplan-Meier survival analysis of xenografts (A) IV and (B) V, demonstrating percent surviving (vertical axis) from the start of treatment (horizontal axis represents days of treatment) with rapamycin (n = 5) or vehicle (n = 5). Median survival of each arm and P values, determined by log-rank test, are indicated.