DKO and Srf Pf4-cKO megakaryocytes have distinct gene expression profiles. (A) Heat maps displaying the differential gene expression patterns of megakaryocytes from the indicated genotypes. Red color represents elevated expression while green represents decreased expression compared with the row mean. Genes displayed were selected based on fold changes of 2 or more and FDR adjusted P value < .05 between WT and DKO. (C) Venn diagrams showing genes with fold changes of 2 or more and FDR adjusted P value < .05 for the indicated comparisons. Representative qPCR expression of EGFL7, miR-126, and SPRED1 in megakaryocytes. Values are displayed as log₂ fold change over WT.