Figure 1
Microarray values for KLF9 expression in MM patients correlate with patient response to bortezomib, but not dexamethasone. Expression of KLF9 in patient myeloma cells was determined from gene expression profile arrays that were generated at Millenium Pharmaceuticals from patients before Bortezomib (Bz; n = 163) or dexamethasone therapy (Dex; n = 67), and deposited in the Gene expression omnibus database (GSE9782). Using the dataset annotations, KLF9 expression among responders (R) or nonresponders (NR) within Bz (n = 85 for R, n = 78 for NR) or Dex (n = 28 for R, n = 39 for NR) groups were plotted on the horizontal axis against the log transformed normalized affymetrix expression units on the vertical axis. Probe set numbers correspond to those in supplemental Table 2. P values between R and NR are shown above the corresponding therapy group.

Microarray values for KLF9 expression in MM patients correlate with patient response to bortezomib, but not dexamethasone. Expression of KLF9 in patient myeloma cells was determined from gene expression profile arrays that were generated at Millenium Pharmaceuticals from patients before Bortezomib (Bz; n = 163) or dexamethasone therapy (Dex; n = 67), and deposited in the Gene expression omnibus database (GSE9782). Using the dataset annotations, KLF9 expression among responders (R) or nonresponders (NR) within Bz (n = 85 for R, n = 78 for NR) or Dex (n = 28 for R, n = 39 for NR) groups were plotted on the horizontal axis against the log transformed normalized affymetrix expression units on the vertical axis. Probe set numbers correspond to those in supplemental Table 2. P values between R and NR are shown above the corresponding therapy group.

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