Effect of A11 on spontaneous metastasis of LLC. (A) It illustrates the treatment protocols in the spontaneous lung metastasis model. LLC indicates Lewis lung carcinoma. (B) Mean number of surface nodules per lung. (C) Mean volume of nodules per lung. (D) Representative histologic evidence from tumor sections of the different groups. (i-ii) 13CG2. (i) ×40; (ii) ×200. (iii-iv) A11. (iii) ×40; (iv) ×200. 13CG2 indicates control scFv Ab; n = 8, *P < .01.