Figure 4
Figure 4. VEGFR1 stimulation redistributes MKs to the vascular niche. Mice were administered either VEGF-A165, PlGF-2, VEGF-E (100 μg/kg intraperitoneally), or vehicle (PBS) each day for 4 consecutive days before femurs were excised for bone marrow histology. (A) Quantification of MKs per field of view, and (B) quantification of the number of MKs adjacent to sinusoidal vessels; n = 5-6 animals per group. Data are expressed as mean ± SEM; ***P < .001 compared with control.

VEGFR1 stimulation redistributes MKs to the vascular niche. Mice were administered either VEGF-A165, PlGF-2, VEGF-E (100 μg/kg intraperitoneally), or vehicle (PBS) each day for 4 consecutive days before femurs were excised for bone marrow histology. (A) Quantification of MKs per field of view, and (B) quantification of the number of MKs adjacent to sinusoidal vessels; n = 5-6 animals per group. Data are expressed as mean ± SEM; ***P < .001 compared with control.

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