BAY73-6691 reduces leukocyte adhesion and extravasation via a cGMP-dependent pathway. (A) Leukocyte rolling, (B) adhesion, and (C) extravasation in TNF-α–treated C57BL6 WT mice after administration of vehicle or BAY73-6691, in the presence or absence of KT5823 (n = 4-10 mice per group; *P < .05, ***P < .001, compared with vehicle alone; #P < .05, ###P < .001, compared with BAY73-6691 alone).