Sequential MRD monitoring during follow-up in inv(16) patients. (A) Mantel-Byar estimate of relapse (%) in patients with > 50 CBFB-MYH11 copies in BM. (B) Mantel-Byar estimate of survival (%) from CR in patients with > 50 CBFB- MYH11 copies in BM. (C) Mantel-Byar estimate of relapse (%) in patients with > 10 CBFB- MYH11 copies in PB. (D) Mantel-Byar estimate of survival (%) from CR in patients with > 10 CBFB- MYH11 copies in PB.